Inflammation can be described as a complex biological response of the tissue in the body to harmful stimuli. These stimuli can be seen in the form of damaged cells, injury, irritants, stress, toxins, or pathogens. 

The inflammation process is introduced to remove the initial cause of injury, remove damaged cells, and begin repair of tissue. The symptoms of inflammation may include pain, heat, swelling, redness, as well as the loss of function. Inflammation is a vital immune response that not only aids the destruction of harmful stimuli but also plays a primary role in the survival of an organism.

Although the normal inflammation response is important to the body’s effective functioning, chronic inflammation, which lasts for a longer time, can have long term detrimental effects on health. 


The use of CBD for inflammation

Some studies have discovered that CBD can stimulate the PPAR (or peroxisome proliferator-activated receptor), which helps in reducing the number of inflammatory substances while increasing antioxidants. CBD also regulates the production of inflammatory prostaglandin, which supports common issues such as menstrual pains.

Pain is an unfavorable symptom of inflammation. CBD can help in blocking the pain messages to the brain that inflammation causes just by interacting with the glycine receptors. 

A study in 2017 also revealed that CBD had a positive effect on the pain associated with damaged nerves and joints when administered to the inflamed joints of rats with osteoarthritis.


How does CBD help in treating inflammation conditions?

Via interaction with the bodies endocannabinoid system (both CB1 and CB2 receptors), CBD supports the improved function of the body’s nervous system. In turn, this helps to reduce some of the symptoms of inflammation as well as some of the factors that tend to make inflammation worse, such as stress and reduced metabolic rate.  


Researchers have also indicated that CBD affects immune responses and host resistance, disturbing the balance between the cytokines produced by T-helper subsets, and hence interacting with the initiation process and inflammation resolution.


The Effect of CBD on Inflammation

How does science say it works?

According to a study published in August 2000, the authors revealed that CBD, via its combined anti-inflammatory and immunosuppressive actions, had a robust and anti-arthritic effect. The study involved a 5mg/kg oral daily or 25mg/kg intraperitoneal administration of CBD to mice, and it showed that the compound was greatly beneficial in regulating the progression of the disease.

In July 2016, another study was conducted, which revealed topical CBD applications as having positive therapeutic potential for relief of inflammation and arthritis pain-related behaviors in rats, without any notable side effects.


The benefits of using CBD for inflammation 

There are many benefits of using CBD for inflammation. Some of these benefits are:

  • Reduced dependency on taking opiates for pain relief;
  • Reduced requirement for taking NSAIDs, which are well known to be the cause of the gastric ulcer; and
  • Fewer side effects compared to the use of opiates and steroids.

If you have experience using CBD for treating inflammation, we would love to hear from you about how it has helped as well as the scientific studies you read or took part in that validate the claims. You can email us at

Ian Parkes

Ian has been writing for a number of high growth industries for the past decade. Having plied his trade in the craft beer industry, Ian drew parallels between that and the world of CBD and soon became fascinated. Ian enjoys writing about innovation in the industry, particularly as it relates to the development of the leading brands.

See all posts by Ian Parkes

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