The Use Of CBD In Supporting Anemia And Low Blood Pressure In Women
Description: Anemia is a condition that can limit you from engaging in many activities. But don't worry because CBD can...
Read moreOne of the most common reasons people use CBD is to help treat various medical conditions and, more specifically, to treat different types of pain from those conditions. But how does CBD actually work to reduce pain, you ask? Well, it all starts with the body’s endocannabinoid system.
The endocannabinoid system is a biochemical communication system in our bodies that helps regulate everything from nerve function and muscle coordination to immunity and blood circulation. It’s made up of two types of cannabinoid receptors, CB1 and CB2, which both promote neural sensitivity and efficacy. CB1 receptors are found in the brain and central nervous system and influence our emotions, mood, appetite, coordination, movement, and pain. CB2 receptors are found primarily in the immune system, but also in peripheral organs and tissues of the muscular and cardiovascular systems.
While our body naturally produces endocannabinoid compounds that react with the CB1 and CB2 receptors and help keep the body balanced, when we experience injury, disease or other deficiency of endocannabinoids, the compounds found in CBD, called phytocannabinoids, can help pick up the slack. But instead of interacting directly with CB1 and CB2 receptors like THC compounds, CBD compounds simply help to stimulate the receptors and get the body to recognize and use more of its natural cannabinoids and neurotransmitters. (Hence, no “high”.)
CBD’s effect on pain depends on the type of pain: nociceptive, neuropathic or central pain.
CBD most readily affects nociceptive pain by recruiting CB2 receptors in the immune system. It blocks the inflammatory signals, or mediators, sent to the brain in order to stop the onset of inflammation after damage, and also switches macrophage repair cells from instigating inflammation to reducing it. CBD further mitigates nociceptive pain by diminishing the pain signals sent to the brain through neurotransmitters and CB1 receptors. Effectively, it amplifies the activity of inhibitory receptors for those neurotransmitters, making fewer pain signals reach the brain so the body doesn’t feel as much of it. A few studies on mice and rats have found very favorable results in CBD’s effect on chronic pain and inflammation.
Because neuropathic pain comes from the nervous system and isn’t necessarily localized to an easily targetable area, it’s more difficult to treat. Where CBD has been found to be helpful is in limiting the expression of certain pain and inflammatory mediators (see: CB2 receptors!) that spike when treating neuropathic conditions (e.g. multiple sclerosis, Parkinson’s disease, HIV, shingles), coupled with its increased activation of serotonin receptors (CB1!). Higher serotonin levels naturally make us feel better, happier and less acutely aware of or affected by pain.
Lastly, we have central pain. As the blanket category encompassing many varied types of pain, central pain, and CBD’s impact on it, is the least studied at this point. A 2018 study, however, did find significant positive effects of using cannabis products in patients with fibromyalgia.
Separately, studies have also found supporting results in CBD’s effectiveness in treating drug addiction as well as reducing the likelihood of potential addiction to opioids when using them to treat pain.
The CBD wave is still new, and the data and scientific research around its effects are in early stages. But already there is much evidence pointing to its highly positive impact on inflammatory pain, with increasing data supporting its beneficial effects on neuropathic and central pain, and all data pointing to CBD having no adverse effects. The most common conditions finding notable impacts thus far are:
To see more studies’ findings on specific conditions, see this list.
As more and more studies come out, we will continue to update our resources and bring you the best information available.
CBD World News is part of an active community, working to enhance our understanding of the benefits of CBD. You can become an active part of that community too, by taking part in our collaborative research. We are interested in finding out who is using CBD, how it is used, and what it is used for?
Taking part in this research will help bring the good word of CBD to life and help people all over the world discover the benefits of cannabinoids.